Desktop Molecular Distillation Apparatus-Short Path Molecular Distillation System — Glass-Anvore Scientific-Lab & Industrial Process Equipment

Bench-top Short-Path Molecular Distillation Apparatus

0.05 m² Wiped-Film Evaporation · Throughput 0.1–2.0 L/h · Vacuum < 10 Pa · RT–200 °C · Gentle Separation for Heat-Sensitive Materials

The AV-F50 is a bench-top short-path molecular distillation apparatus built around a Ø 50 mm borosilicate glass evaporator body. Molecular distillation is a special liquid–liquid separation technology: under high vacuum (below 10 Pa), the mean free path of vapor molecules exceeds the distance between the evaporation and condensation surfaces, so components are separated by their differences in evaporation rate — not by boiling.

Feed (0.1–2.0 L/h) is distributed onto the heated wall (RT–200 °C) by PTFE / 304 stainless steel wipers spinning at up to 450 rpm, forming a turbulent liquid film thinner than 0.5 mm. Light components evaporate instantly and condense on the short-path internal condenser for collection as the light fraction; heavier components flow down the wall into the heavy fraction receiver. An external condenser with cold trap recovers solvents and protects the vacuum pump.

Compared with conventional short-path stills, the AV-F50 offers shorter residence time, lower processing temperature and continuous operation without breaking vacuum — an ideal turn-key solution for lab-scale and pilot purification of high-boiling, heat-sensitive and easily oxidized materials.

Desktop Molecular Distillation Apparatus

Key Advantages

Gentle Low-Temperature Separation — Operates far below the boiling point with a short residence time — ideal for high-boiling, heat-sensitive and easily oxidized materials.
High Vacuum, Below 10 Pa — Ultimate vacuum below 10 Pa (no-load) protects materials from oxidation and lowers the operating temperature.
Thin Film, High Heat Transfer — Wipers spread the liquid into a film < 0.5 mm thick, giving high evaporation efficiency with no bubbling or foaming.
Effective Degassing & Deodorizing — Efficiently strips organic solvents and odors — highly effective for desolvating solvent-extracted liquids.
Multi-Stage Selective Separation — Selectively evaporates target products and removes impurities; multi-stage operation separates 2+ components simultaneously.
Corrosion-Resistant Wetted Parts — Wiper system of PTFE + 304 stainless steel; fluoroelastomer (optionally PTFE) gaskets throughout for excellent sealing and chemical resistance.
Turn-Key Bench-top Design — Integrated feed tank (preheatable), metering pump, heating, cooling, external condenser and receivers on one compact frame — plug and play.
Scalable & Customizable — Multiple evaporation areas for bench and pilot scale; larger areas available on request. Preheating temperature adjustable.
Pure Physical Separation — Non-toxic, harmless, pollution-free and residue-free — yields clean, safe products with no solvent carry-over.

Product Features

Feature	Benefit
Short-path molecular distillation at < 10 Pa	Molecule mean free path exceeds evaporation–condensation gap for true molecular separation
PTFE + 304 SS wiper system, ≤ 450 rpm	Turbulent film < 0.5 mm; high heat transfer, no hot spots
Heating jacket RT – 200 °C	Wide temperature window matched to thermally sensitive products
Preheatable 1 L feed tank with metering pump	Adjustable feed rate 0.1–2.0 L/h and preheat temperature
Internal condenser 0.1 m² + external condenser & cold trap	Efficient light-fraction capture, solvent recovery and pump protection
Separate 250 mL light / heavy fraction receivers	Clean split of distillate and residue for easy analysis
Continuous operation without breaking vacuum	Uninterrupted processing for higher productivity
All-glass borosilicate construction	Full process visibility; corrosion resistant and easy to clean
Fluoroelastomer / optional PTFE sealing	Excellent airtightness; PTFE option for aggressive media
Bench / pilot / custom evaporation areas	Seamless scale-up path from feasibility study to pilot line

Technical Specifications

Additional evaporation areas for pilot and production scale available on request — contact sales for tailored models.

Parameter	AV-F50
Evaporator inner diameter	50 mm
Evaporation area	0.05 m²
Condensation area	0.1 m²
Feed tank volume	1 L (preheating optional, adjustable)
Throughput	0.1 – 2.0 L/h
Wiper motor power	60 W
Max rotation speed	450 rpm
Light fraction receiver	250 mL
Heavy fraction receiver	250 mL
External condenser / cooling device / heating device	Standard
Operating vacuum	< 10 Pa (no-load ultimate vacuum)
Heating temperature	Room temperature – 200 °C
Dimensions (main body, without trough)	1100 × 500 × 1300 mm (L × D × H)
Dimensions (with trough)	1500 × 500 × 1300 mm (L × D × H)
Power supply	Voltage customizable (110V / 220V / 230V / 380V, 50/60Hz)

System Structure

Stage 1 · Feed & Preheating
Material is charged into the 1 L feed tank (optional preheating with adjustable temperature) and delivered at 0.1–2.0 L/h by the metering pump, ensuring a stable, controlled feed to the evaporator.
Stage 2 · Wiped-Film Evaporation
Inside the Ø 50 mm glass body, PTFE / 304 SS wipers (up to 450 rpm, 60 W) spread the feed into a film < 0.5 mm on the heated wall (RT–200 °C). Under a vacuum below 10 Pa, the mean free path of vapor molecules exceeds the gap to the internal condenser: light components evaporate and travel directly to the cold surface, while heavy components stay in the liquid film.
Stage 3 · Separation & Collection
Condensed light fraction drains into the 250 mL light receiver as purified distillate; the concentrated heavy fraction flows down into its own 250 mL receiver. The external condenser and cold trap recover solvents and shield the vacuum pump, enabling continuous multi-stage separation of two or more components without breaking vacuum.

Applications

Fine chemicals — — purification of aromatic (essential) oils, polymer intermediates, lanolin extraction
Pharmaceuticals — — extraction of natural vitamins A & E, production of amino acid and glucose derivatives
Food industry — — refined fish oil, fatty acid deacidification, high-carbon alcohol purification, mixed oil fractionation
Cannabinoids & botanicals — — CBD / hemp oil and herbal extract purification and decolorization
Petrochemicals — — heavy fraction upgrading and specialty base oil refining
Daily chemicals & environmental protection — — fragrance purification, solvent recovery, waste stream concentration