Vacuum Short Path Distillation Equipment

Separation for Heat-Sensitive Materials

The AV-F100 is a pilot-scale short-path molecular distillation apparatus built around a Ø 100 mm borosilicate glass evaporator body with 0.15 m² of evaporation area and 0.25 m² of condensation area. Processing 0.5–5.0 L/h into 2 L receivers, it is the flagship of the Anvore glass molecular still family (AV-MD-50 / AV-MD-60 / AV-F80 / AV-F100) — the workhorse that carries a validated lab process into pilot production.

Molecular distillation is a special liquid–liquid separation technology: under high vacuum (below 10 Pa), the mean free path of vapor molecules exceeds the distance between the evaporation and condensation surfaces, so components are separated by their differences in evaporation rate — not by boiling. A 120 W PTFE / 304 SS wiper system (up to 450 rpm) spreads the feed into a turbulent film thinner than 0.5 mm on the heated wall (RT–200 °C); light components evaporate and condense on the internal condenser, while heavy components flow to a separate 2 L receiver. A built-in cold trap protects the vacuum pump, and an external condenser is available as an option.

Compared with conventional short-path stills, the AV-F100 delivers shorter residence time, lower processing temperature and continuous operation without breaking vacuum — a true plug-and-play, turn-key solution for pilot purification of high-boiling, heat-sensitive and easily oxidized materials.

Key Advantages

• Gentle Low-Temperature Separation — Operates far below the boiling point with a short residence time — ideal for high-boiling, heat-sensitive and easily oxidized materials.
• High Vacuum, Below 10 Pa — Ultimate vacuum below 10 Pa (no-load) protects materials from oxidation and lowers the operating temperature.
• Thin Film, High Heat Transfer — Wipers spread the liquid into a film < 0.5 mm thick, giving high evaporation efficiency with no bubbling or foaming.
• Flagship Pilot Capacity — 0.15 m² evaporation area, 0.5–5.0 L/h throughput and 2 L light / heavy receivers (customizable) — top of the glass molecular still line.
• Effective Degassing & Deodorizing — Efficiently strips organic solvents and odors — highly effective for desolvating solvent-extracted liquids.
• Multi-Stage Selective Separation — Selectively evaporates target products and removes impurities; multi-stage operation separates 2+ components simultaneously.
• Corrosion-Resistant Wetted Parts — Wiper system of PTFE + 304 stainless steel; fluoroelastomer (optionally PTFE) gaskets throughout for excellent sealing and chemical resistance.
• Cold Trap Standard, Options Galore — Built-in cold trap and cooling device; optional external condenser, preheatable feed vessel and custom receiver sizes.
• Pure Physical Separation — Non-toxic, harmless, pollution-free and residue-free — yields clean, safe products with no solvent carry-over.

Working Principle

Feed is metered (0.5–5.0 L/h) from a preheatable 1 L vessel onto the heated wall of the Ø 100 mm glass evaporator. Rotating PTFE wipers spread it into a film < 0.5 mm; under a vacuum below 10 Pa, light molecules fly directly onto the internal condenser (mean free path > evaporator–condenser gap) while heavy molecules keep flowing down the wall — light and heavy fractions are collected separately, with no boiling and no thermal stress.

Technical Specifications

• Additional evaporation areas for pilot and production scale available on request — contact sales for tailored models.

Applications

• Fine chemicals — — purification of aromatic (essential) oils, polymer intermediates, lanolin extraction
• Pharmaceuticals — — extraction of natural vitamins A & E, production of amino acid and glucose derivatives
• Food industry — — refined fish oil, fatty acid deacidification, high-carbon alcohol purification, mixed oil fractionation
• Cannabinoids & botanicals — — CBD / hemp oil and herbal extract purification and decolorization
• Petrochemicals — — heavy fraction upgrading and specialty base oil refining
• Daily chemicals & environmental protection — — fragrance purification, solvent recovery, waste stream concentration