LC-MS Membrane Nitrogen Generator

The AV-MNG-30L1 is a high-flow membrane nitrogen generator purpose-built to deliver continuous, high-purity nitrogen to LC-MS mass spectrometers (single gas line) from leading brands — Agilent and Thermo Fisher.

It separates nitrogen from compressed air using hollow-fiber membrane technology: because oxygen, carbon dioxide and water vapor permeate through the fiber walls faster than nitrogen, a continuous stream of dry, clean nitrogen is produced on-site — completely eliminating the cost, hazard and downtime of high-pressure gas cylinders.

The unit integrates the air compressor, water separation, multi-stage precision filtration, membrane separation and buffer storage into a single compact cabinet. Plug it in, connect one gas line to your mass spectrometer, and enjoy 24/7 worry-free nitrogen supply for nebulizer gas, curtain gas and collision gas.

Key Advantages

• Eliminates Gas Cylinders Continuous on-site N₂ generation — no rental, no delivery, no cylinder-swapping downtime, no safety hazards.
• Zero Consumables Membrane separation needs no desiccant or catalyst replacement — the lowest running cost over the machine's life.
• Built-in Compressor No external air supply needed; engineered for 24-hour continuous duty.
• Ultra-Pure, Dry Gas Particles < 0.01 µm, pressure dew point < −40 °C, no droplet or phthalate residue — safe for sensitive MS analysis.
• Real-Time Purity Display Onboard analyzer shows N₂ purity (95 – 99.99%) clearly for instant quality confidence.
• Fast Gas Production Nitrogen on demand in ≤ 3 minutes; capacity can be expanded easily.
• Smart Diagnostics Program-controlled self-diagnosis, service reminders and filter failure warning reduce maintenance guesswork.
• Dual Adjustable Pressure Output up to 105 psi, freely adjustable to match your instrument requirement.
• Compact & Mobile Highly integrated modular design saves lab space; lockable caster wheels make repositioning effortless.

Product Features

Technical Specifications

• Custom flow rates and purity (99% / 99.9% / 99.99% / 99.999% / 99.9999%) available on request — contact sales for tailored models.

System Structure

• Stage 1 · Air Compression & Pretreatment
• Ambient air enters the built-in compressor (24/7 duty). A water separator removes moisture, then a multi-stage ultra-precision filter (< 0.01 µm) cleans the air stream, with a filter failure warning to guarantee protection of the membrane module.
• Stage 2 · Hollow-Fiber Membrane Separation (Core)
• Clean compressed air enters the hollow-fiber membrane module. Oxygen, CO₂ and water vapor permeate through the fiber walls rapidly and are vented to atmosphere, while nitrogen passes through and is collected as product gas. No switching valves, no consumables — gas is ready in < 3 minutes.
• Stage 3 · Nitrogen Delivery & Quality Control
• The N₂ buffer tank stabilizes pressure (safety valve fitted), the onboard purity analyzer displays 95 – 99.99% in real time, and the dual pressure regulator delivers up to 105 psi through a single gas line to the LC-MS nebulizer, curtain gas and collision gas ports.

Applications

• Mass spectrometry — LC-MS, single gas line (Agilent, Thermo Fisher compatible)
• Nebulizer gas, curtain gas, collision gas, auxiliary gas — stable supply for high-throughput analysis
• Pharmaceutical & bio-analytical labs — method development and routine quantification
• Food safety & environmental testing — pesticide residue and contaminant analysis
• Academic & research institutes — chemistry, life science, proteomics, metabolomics
• Clinical & forensic labs — high-throughput screening applications